Comprendre le fonctionnement des organismes vivants, telle est l’ambition du Centre de biologie intégrative (CBI), à Toulouse. Pour atteindre cet objectif, le CBI développe des approches multidisciplinaires, multi-échelles des molécules isolées aux organismes entiers et aux sociétés animales, et utilise de nombreux organismes modèles, des bactéries à l'homme.
https://goo.gl/maps/Tq5uBW1EEkPrg49p7
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Prof. Jody Rosenblatt will present exciting new findings in a seminar entitled “When cells lose their spark: a surprising new role for electricity in cell extrusion.”
Jody Rosenblatt is Professor of Cell Biology at King’s College London and Group Leader at The Francis Crick Institute. Her laboratory has made major contributions to our understanding of epithelial tissue dynamics, particularly the process of epithelial cell extrusion. This mechanism allows epithelial tissues to remove cells while preserving barrier integrity, helping tissues maintain constant cell numbers during homeostasis, renewal and stress.
Over the past years, the Rosenblatt lab has revealed how epithelial tissues integrate mechanical forces, cell crowding, cell death, division and extrusion to maintain tissue architecture. Their work has helped establish cell extrusion as a fundamental process in epithelial biology, with implications for development, tissue homeostasis, inflammation and cancer.
In this keynote seminar, Prof. Rosenblatt will discuss new findings uncovering an unexpected role for bioelectricity in epithelial cell extrusion. This work opens exciting perspectives on how electrical signals may cooperate with mechanical and biochemical cues to control cell elimination and tissue organisation.
The keynote seminar will be followed by a poster session with coffee and snacks, providing an opportunity for informal discussions and exchanges with the broader scientific community.
Sponsored by SFRB2S
Comprendre le fonctionnement des organismes vivants, telle est l’ambition du Centre de biologie intégrative (CBI), à Toulouse. Pour atteindre cet objectif, le CBI développe des approches multidisciplinaires, multi-échelles des molécules isolées aux organismes entiers et aux sociétés animales, et utilise de nombreux organismes modèles, des bactéries à l'homme.
https://goo.gl/maps/Tq5uBW1EEkPrg49p7
Financé par