Les avancées scientifiques de la recherche toulousaine en biologie et biotechnologie pour la santé
24 – 25 novembre 2025
Amphithéâtre Marthe Condat, Université de Toulouse
Programme
Lundi 24 novembre
8:30-8:50 : Welcome
8:50 – 9:00 : Introduction Abdelhadi Saoudi, SFR-B2S Director
9:00 – 10:00 :
Keynote speaker – Andaine SEGUIN-ORLANDO
Associate Professor at the University of Toulouse and CAGT – Chair: Isabelle Saves
« An ancient DNA perspective on human (pre)history »
10:00– 11:00 : Session 1: Chairs to be confirmed
- S1- Pierre Cordelier – CRCT – “Cytidine Deaminase Resolves Replicative Stress and Protects Pancreatic Cancer from DNA-Targeting Drugs.”
- S2- Françoise Guéraud – TOXALIM – “Effects of sodium nitrite reduction, removal or replacement on cured and cooked meat for microbiological growth, food safety, colon ecosystem, and colorectal carcinogenesis in Fischer 344 rats.”
- S3- Jean-Denis Pedelacq – IPBS – “Catalytic Cycle of Type II 4′-Phosphopantetheinyl Transferases.”
- S4- Jean-Charles Guéry – Infinity – “Altered X chromosome inactivation of the TLR7/8-locus is associated with enhanced IFN signature in pDCs in systemic sclerosis.”
11:00 – 11:30 – Coffee break
11:30 – 12:30 : Session 2: Chairs to be confirmed
- S5- Alice Davy – CBI – “Acute dietary methionine restriction highlights sensitivity of neocortex development to metabolic variations”
- S6- Floriant Bellvert – TBI – “Pivotal role of exogenous pyruvate in human natural killer cell metabolism.”
- S7- Gilles Foucras– IHAP – “Characterisation of inborn errors of immunity in cattle identified through mass genomic identification”
- S8- Bastien Gerby – CRCT – “Stem cell-like reprogramming is required for leukemia-initiating activity in B-ALL.”
12:30 – 14:00 – Lunch break
14:00 – 14:45 : Session 3: Chairs to be confirmed
- S9- Barbara Garmy-Susini – I2MC – “15-Lipoxygenase promotes resolution of inflammation in lymphedema by controlling Treg cell function through IFN-β.”
- S10- Audrey Goman – IRSD – “Conserved bacterial enzymes fuel a lipid-based strategy for immune evasion and microbial warfare.”
- S11- Jenny Paupert – Restore –“A computational model reveals an early transient decrease in fiber cross-linking that unlocks adult regeneration.”
14:45 – 15:45 : Session SFR-B2S Young researchers (selected on abstract) Chairs to be confirmed
- SD1- Cassandra Konan – CBI – “Exploring the role of EPHRIN-B1 in the human brain development using human cerebral organoids.”
- SD2- Cédric Fabre – CRCT – “Overcoming T cell exclusion in PDAC: Periostin as a therapeutic target?”
- SD3- Nadine Gheziel – IRSD – “Prenatal Stress triggers tactile and behavioral deficits in offspring through peripheral sensory neurons neurodevelopmental perturbations.”
- SD4- Virginie Stevenin – IPBS – “Ubiquitination-dependent manipulation of host recycling pathways by the intracellular bacteria Salmonella.”
- SD5- Margaux Lalaurie – TOXALIM – “The interaction between bread and meat: the mycotoxin deoxynivalenol increases the genotoxicity of heme iron.”
15:45 – 16:15 – Coffee break
16:15 – 17:15 : Session 4: Chairs to be confirmed
- S12- Jean Monlong – IRSD – “Building a human pangenome reference to improve genomic studies”
- S13- Ludovic Martinet – CRCT – “NK cells with adhesion defects and reduced cytotoxic functions are associated with a poor prognosis in multiple myeloma.”
- S14- Sebastien Britton – IPBS – “Identification of the main barriers to Ku accumulation in chromatin.”
- S15- Aurora Pignata – Infinity – “Tissue resident memory CD4+ T cells infiltrate the CNS in progressive multiple sclerosis and contribute to chronic autoimmunity in mice.”
17:15-17:30 – Closure day 1
Mardi 25 novembre
9:00 – 10:00 :
Keynote speaker Nicolas GAUDENZIO –
Research director in immunology at Inserm and Head of the « Neuronal regulation of the immune responses » group at Infinity institute, Toulouse
« Neuro-immune interactions in allergy from fetal imprinting to disease development »
10:00 – 11:00 : Session 5: Chairs to be confirmed
- S16 – Julien Viaud – I2MC – “MTM1-mediated production of phosphatidylinositol 5-phosphate fuels the formation of podosome-like protrusions regulating myoblast fusion”
- S17- Philippe Rousseau – CBI – “Interplay between the Xer recombination system and the dissemination of antibioresistance in Acinetobacter baumannii.”
- S18- Pauline Schmitt – IPBS – “TL1A is an epithelial alarmin that cooperates with IL-33 for initiation of allergic airway inflammation. ”
- S19- Isabelle Ader – Restore – “Identification of functional cellular markers related to human health, frailty and chronological age.
11:00 – 11:30 – Coffee break
11:30 – 12:30 : Session 6: Chairs to be confirmed
- S20- Nathalie Bastié – CBI – “Sister chromatid cohesion halts DNA loop expansion.”
- S21- Nicolas Blanchard – Infinity – “Toxoplasma gondii infection and chronic IL-1 elevation drive hippocampal DNA double-strand break signaling, leading to cognitive deficits.”
- S22- Marine Huillet – TOXALIM – “Pharmacological activation of constitutive androstane receptor induces female- specific modulation of hepatic metabolism.”
- S23- Stéphanie Gayral – I2MC – “PI3KCIIα-Dependent Autophagy Program Protects From Endothelial Dysfunction and Atherosclerosis in Response to Low Shear Stress in Mice.”
12:30 – 14:00 – Lunch Break
14:00– 15:00 : Session 7: Chairs to be confirmed
- S24- Sebastien Nouaille – TBI – “When translation elongation is impaired, the mRNA is uniformly destabilized by the RNA degradosome, while the concentration of mRNA is altered along the molecule.”
- S25- Olivier Calvayrac – CRCT – “Farnesyltransferase inhibition overcomes oncogene-addicted non-small cell lung cancer adaptive resistance to targeted therapies.”
- S26- Christophe Guilhot – IPBS – “Evolution of tuberculosis bacilli in response to different selective pressures: the role of the PhoPR two-component regulatory system.”
- S27- Emilie Dordet-Frisoni – INTHERES– “The interplay between mobilome and resistome in Staphylococcus aureus.”
15:00 – 16:00 : Session SFR-B2S Young researchers (selected on abstract) : Chairs to be confirmed
- SP1- Lilibeth Torres – CBI – “A microbial Genome-Wide Association Study identifies new potential genes involved in regulating hypermucoviscosity in Klebsiella pneumoniae .”
- SP2- Alban Ricard – CRCT – “Relationship between the E3 ubiquitin ligase TRIP12 and the Mediator of DNA damage checkpoint MDC1 : its impact on DNA Damage Response.”
- SP3- Juliana Boukhaled – I2MC – “Altered Metabolic Profile is Associated with Cardiac remodelling and Dysfunction
in Chronic Kidney Disease .” - SP4- Rim Khanfour – INTHERES – “Segment-Specific Activity and Effects on the Gut Microbiota and Resistome of oxytetracycline per os in Pigs.”
- SP5- Emma Valdevit – Infinity – “Human T follicular regulatory cells are composed by two layers of heterogeneity.”
16:00 – 16:30 – Coffee break
16:30 – 17:30 : Session 8 : Chairs to be confirmed
- S28- Thanina Medjbeur – IRSD – “Comparative analysis of dietary iron modulation in a murine model of colitis.”
- S29- Lionel Dahan – CBI – “Ventral tegmental area dopamine projections to the hippocampus trigger long-term potentiation and contextual learning.”
- S30- Isabelle Lamsoul – Infinity – “Fine-tuning levels of filamins an and b as a specific mechanism sustaining Th2 lymphocyte functions.”
- S31- Caroline Conte – I2MC – “Macromolecular Complex Including MLL3, Carabin and Calcineurin Regulates Cardiac Remodeling.”
17:30 : conclusion Isabelle Saves, SFR-B2S Deputy Director
Comité d'organisation
Lilian Basso – Infinity
Laure David – IRSD
Natalia Smirnova – I2MC
Carine Froment – IPBS
Roxana Khazen – CRCT
Abdelhadi Saoudi – Infinity
Isabelle Saves – CBI-IPBS
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Localisation
Université de Toulouse
118 route de Narbonne
31400 Toulouse
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